Proteins

- "Cyclic hyperalimentation" - an optimal technique for preservation of visceral protein mass.

- 2005 AAPS biotechnology conference open forum on aggregation of protein therapeutics - panel discussion June 5-8, 2005 San Francisco, CA.

- A cAMP-dependent regulatory protein for RLC-a myosin kinase catalyzing the phosphorylation of scallop smooth muscle myosin light chain. A cAMP-dependent regulatory protein which modulates the phosphorylation of scallop myosin regulatory light chain-a (RLC-a) by RLC-a myosin kinase (aMK)...

- A comparative study of bioorthogonal reactions with azides. Detection of metabolites and post-translational modifications can be achieved using the azide as a bioorthogonal chemical reporter. Once introduced into...

- A complete algorithm to resolve ambiguity for intersubunit NOE assignment in structure determination of symmetric homo-oligomers. Assignment of nuclear Overhauser effect (NOE) data is a key bottleneck in structure determination by NMR. NOE assignment resolves the ambiguity as to which...

- A complete microfluidic screening platform for rational protein crystallization.

- A fungal laccase, its properties and reconstitution from its protein and copper.

- A general strategy for the assignment of aliphatic side-chain resonances of uniformly 13C,15N-labeled large proteins. A general strategy is proposed to assign aliphatic side-chain resonances of large 13C,15N-labeled proteins without deuteration, using 4D 13C,15N-edited NOESY...

- A hidden Markov model for predicting protein interfaces. Protein-protein interactions play a defining role in protein function. Identifying the sites of interaction in a protein is a critical problem for...

- A mechanism for the formation of fibrils from protein molecules.

- A network-based analysis of polyanion-binding proteins utilizing human protein arrays. The existence of interactions between many cellular proteins and various polyanionic surfaces within a cell is now well established. The functional role of...

- A new approach to the chemical synthesis of keto-proteins. To increase the versatility of protein-conjugation, an orthogonal protection strategy is described, which enables the efficient synthesis of keto-proteins...

- A new detection algorithm for image analysis of single, fluorescence-labeled proteins in living cells. A new algorithm is presented for the detection of single, fluorescence-labeled proteins in the analysis of images from living cells. It is especially suited...

- A new mutation of the fukutin gene in a non-Japanese patient. Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome, and muscle-eye-brain disease are clinically similar autosomal recessive...

- A new plakalbumin-like protein.

- A novel high resolution Calpha--Calpha distance dependent force field based on a high quality decoy set. This work presents a novel C(alpha)--C(alpha) distance dependent force field which is successful in selecting native structures from an ensemble of high...

- A novel mutation in JARID1C gene associated with mental retardation. X-linked mental retardation (XLMR) is an extremely heterogeneous condition that account for 15-25% of all mentally retarded patients. The number of genes...

- A polymer scaffold for protein oligomerization. We report the design and synthesis of well-defined polymers for the noncovalent oligomerization of proteins. The reported scaffolds, which were generated by...

- A role of mixed-function oxidation reactions in the accumulation of altered enzyme forms during aging.

- A simple method to predict protein flexibility using secondary chemical shifts. Protein motions play a critical role in many biological processes, such as enzyme catalysis, allosteric regulation, antigen-antibody interactions, and...