Special Feature

User Panel

My Panel

My Panel

Bookmark Science Articles

Recent News
Bookmark / Share This Science Site

Synthetic glycobiology: Exploits in the Golgi compartment.

Synthetic glycobiology: Exploits in the Golgi compartment. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

  • Abstract Text of This Paper
  • Journal Published
  • MeSH Keywords of This Abstract
  • Chemicals and Substances Used in this Paper
  • Grants and Granting Agency of this Research
  • Database Accession Numbers Used in this Paper
  • Related Papers
  • Related Research Tags
  • Rate this Research Paper
  • Synthetic glycobiology: Exploits in the Golgi compartment. Abstract Text:

    jennifer l czlapinskiJennifer L Czlapinski,carolyn r bertozziCarolyn R Bertozzi,

    The challenge of engineering glycosylation has been confronted by synthetic chemists, biochemists and cell biologists, each with the primary goal of optimizing glycoconjugates for therapeutic applications. In nature, glycans are constructed by glycosyltransferases that are organized in an assembly line in the endoplasmic reticulum and Golgi compartment. Recent insights into the domain architecture, localization and regulation of glycosyltransferases have provided a platform for engineering their position within the secretory pathway and access to substrates. Using this knowledge, glycosyltransferase assembly lines have been redesigned for the production of specific glycan structures using protein engineering and chemical approaches. These efforts epitomize the emerging field of 'synthetic glycobiology'.

    Synthetic glycobiology: Exploits in the Golgi compartment. Publishing Authors By Initials

    jl czlapinskiJL Czlapinski,cr bertozziCR Bertozzi,

    For similar proteins: recombinant proteins research abstracts see: proteins: recombinant proteins research

    PUBMED ID PMID:

    MEDLINE DATE:

    Synthetic glycobiology: Exploits in the Golgi compartment. Journal Published:

    PUBLICATION TYPE: Review

    Journal: Current opinion in chemical biology

    VOLUME: 10

    Page Numbers: 645-51

    Journal Abbreviation:

    ISSN: 1367-5931

    DAY: 23

    MONTH: 10

    YEAR: 2006

    Synthetic glycobiology: Exploits in the Golgi compartment. Information

    Number of References: 49

    LANGUAGE: eng

    NlmUniqueID: 9811312

    Synthetic glycobiology: Exploits in the Golgi compartment. Keywords Mesh Terms:

    KEYWORDS: Recombinant Proteins

    MESH TERMS: genetics

    Chemical & Substance for Abstract: Synthetic glycobiology: Exploits in the Golgi compartment. Information

    Substance Name: Recombinant Proteins

    Registry Number: 0

    Grant and Affiliation Information for Synthetic glycobiology: Exploits in the Golgi compartment.

    AFFILIATION: Department of Chemistry, Howard Hughes Medical Institute, University of California, Berkeley, CA 94720-1460, USA.

    Country: England

    England Research Publication

    AGENCY: United States NIGMS

    GRANT: GM69156

    ACRONYM: GM

    MEDLINETA: Curr Opin Chem Biol

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

    Synthetic glycobiology: Exploits in the Golgi compartment Related Publications

     

    Molecular Station USER Menu

    Welcome to Molecular Station!

    You have to register before you can post on our forums or use our advanced features. Register Now! Its Free and Fast!

    Already registered? Login now below.

    User Name:

    Password:

    Already registered and Forgot your password? Click below to recover it.

    Recover Lost Password

    Join now - it's fast and free!

    Molecular Station is THE largest network of researchers, scientists and science lovers anywhere!

    Research Terms of Usage and Disclaimer
    Home
    Features

    Protocols

    DNA Forum

    Science Forum

    DNA Forum
    Biology Forum

    Science News


    [CaRP] XML error: Invalid document end at line 2

    For more click here:Science News