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Restless legs syndrome and sleep problems in children and adolescents with insulin-dependent diabetes mellitus type 1.

Restless legs syndrome and sleep problems in children and adolescents with insulin-dependent diabetes mellitus type 1. Research Abstract Details 

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  • Restless legs syndrome and sleep problems in children and adolescents with insulin-dependent diabetes mellitus type 1. Abstract Text:

    s happeS Happe,n treptauN Treptau,r zieglerR Ziegler,e harmsE Harms,s happeS Happe,n treptauN Treptau,r zieglerR Ziegler,e harmsE Harms,

    The restless legs syndrome (RLS) occurs in adulthood with a prevalence of 5 to 10% and can be associated with diabetes mellitus. The prevalence in childhood, however, is unknown. We asked consecutive children with type 1 (insulin-dependent) diabetes mellitus as well as their parents and siblings about RLS according to a standardised questionnaire. Altogether, 46 patients (25 female, 12.0 +/- 3.7 years), 50 siblings (29 female, 12.3 +/- 5.5 years) and 75 parents (41 mothers, 40.4 +/- 5.1 years; 34 fathers, 42.5 +/- 5.3 years; 1.3 % with diabetes mellitus) were included. One patient (2.2%), one sibling (2.0%), and 14 parents (18.7%) were diagnosed as having RLS. Disturbances of sleep initiating, sleep maintenance and daytime tiredness were similar in patients and siblings. There was a significant association of higher HbA1c values (mean 7.7 +/- 2.2%) with sleep initiating problems. The mean dose of international units of insulin/kg body weight/day (0.79 +/- 0.26 IU) was not associated with the presence of RLS or sleep problems. To conclude, there seems to be no association of diabetes mellitus type 1 with RLS in children and adolescents. However, there is a relationship between diabetes and sleep disturbances and an optimally controlled diabetes mellitus might be an important factor for an improved sleep initiation.

    Restless legs syndrome and sleep problems in children and adolescents with insulin-dependent diabetes mellitus type 1. Publishing Authors By Initials

    s happeS Happe,n treptauN Treptau,r zieglerR Ziegler,e harmsE Harms,s happeS Happe,n treptauN Treptau,r zieglerR Ziegler,e harmsE Harms,

    For similar investigative techniques: epidemiologic methods: statistics as topic: statistics, nonparametric research abstracts see: investigative techniques: epidemiologic methods: statistics as topic: statistics, nonparametric research

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    Restless legs syndrome and sleep problems in children and adolescents with insulin-dependent diabetes mellitus type 1. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Neuropediatrics

    VOLUME: 36

    Page Numbers: 98-103

    Journal Abbreviation: Neuropediatrics

    ISSN: 0174-304X

    DAY: 16

    MONTH: Apr

    YEAR: 2005

    Restless legs syndrome and sleep problems in children and adolescents with insulin-dependent diabetes mellitus type 1. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 8101187

    Restless legs syndrome and sleep problems in children and adolescents with insulin-dependent diabetes mellitus type 1. Keywords Mesh Terms:

    KEYWORDS: Statistics, Nonparametric

    MESH TERMS: complications

    Chemical & Substance for Abstract: Restless legs syndrome and sleep problems in children and adolescents with insulin-dependent diabetes mellitus type 1. Information

    Substance Name: Insulin

    Registry Number: 11061-68-0

    Grant and Affiliation Information for Restless legs syndrome and sleep problems in children and adolescents with insulin-dependent diabetes mellitus type 1.

    AFFILIATION: Department of Clinical Neurophysiology, University of Göttingen, Germany. shappe@gwdg.de

    Country: Germany

    Germany Research PublicationGermany Research Publication

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    MEDLINETA: Neuropediatrics

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