- Disulfide bridge based PEGylation of proteins. PEGylation is a clinically proven strategy for increasing the therapeutic efficacy of protein-based medicines. Our approach to site-specific PEGylation...
- DTPA-coupled proteins--procedures and precautions. While demonstrating that the cyclic anhydride of diethylenetriaminepentaacetic acid (DTPA) may be used to covalently attach this chelator to proteins, it was...
- Effect of catenation on protein folding stability. Building on previous studies of the effects of covalent linking and backbone cyclization on protein folding stability, a theory is developed for the...