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- Local motions in a benchmark of allosteric proteins. Allosteric proteins have been studied extensively in the last 40 years, but so far, no systematic analysis of conformational changes between allosteric...

- Localization of binding sites in protein structures by optimization of a composite scoring function. The rise in the number of functionally uncharacterized protein structures is increasing the demand for structure-based methods for functional annotation....

- Localization, purification, and biological activity of a new aldosterone-stimulating factor. An aldosterone-stimulating factor (ASF) has been isolated from normal human urine and found to be a glycoprotein with a molecular weight of 26,000 daltons....

- Loss of imprinting at the Dlk1-Gtl2 locus caused by insertional mutagenesis in the Gtl2 5' region. BACKGROUND: The Dlk1 and Gtl2 genes define a region of mouse chromosome 12 that is subject to genomic imprinting, the parental allele-specific expression of...

- Macrocyclic hairpin mimetics of the cationic antimicrobial peptide protegrin I: a new family of broad-spectrum antibiotics. The problems associated with increasing antibiotic resistance have stimulated great interest in newly discovered families of naturally occurring cationic...

- Magnetic susceptibility-induced alignment of proteins in reverse micelles.

- Malignant transformation of squamous epithelium; a cytochemical study with special reference to cytoplasmic nucleic acids and proteins.

- Measurement of deamidation of intact proteins by isotopic envelope and mass defect with ion cyclotron resonance Fourier transform mass spectrometry. After synthesis and folding, proteins undergo many post-synthetic modifications, including cleavage, oxidation, glycosylation, methylation, racemization,...

- Measurements of carbon to amide-proton distances by C-H dipolar recoupling with 15N NMR detection. A new magic-angle spinning NMR method for measuring internuclear distances between a 13C-labeled site and amide protons is described. The magnetization of...

- Mechanism of hepatic ornithine decarboxylase induction by the ornithine decarboxylase-inducing factor isolated from tumor ascites fluid: determination of target cells for the factor in the liver. The effect of the ODC-factor, which was partially purified from ascites fluid of mice bearing Ehrlich ascites hepatoma, on DNA synthesis in the normal mouse...

- Mechanism of incorporation of labeled amino acids into protein.

- Mechanisms of MR signal alteration by acute intracerebral blood: old concepts and new theories. We reviewed the current literature and theories pertaining to the appearance of hemorrhage on MR images. New theories were formulated to explain the etiology...

- Mechanistic studies on the lysine-induced N-formylation of 2,5-dimethyl-p-benzoquinonediimine. 2,5-Dimethyl- p-benzoquinonediimine was used as a model to study the reactivity of p-benzoquinonediimines, the first oxidation intermediates of allergenic...

- Membrane channel formation by antimicrobial protegrins. Protegrins are small, arginine- and cysteine-rich, beta-sheet peptides with potent activity against bacteria, fungi, and certain enveloped viruses. We report...

- Membrane-dependent oligomeric structure and pore formation of a beta-hairpin antimicrobial peptide in lipid bilayers from solid-state NMR. We used solid-state NMR spectroscopy to investigate the oligomeric structure and insertion of protegrin-1 (PG-1), a beta-hairpin antimicrobial peptide, in...

- Metabolic effects of continuous ambulatory peritoneal dialysis. Prospective studies concerning protein, carbohydrate, and lipid metabolism were performed in 19 CAPD patients. After 2-4 months on CAPD the mean nitrogen...

- Method for real-time monitoring of protein degradation at the single cell level.

- Micro-identification of amino-terminal acetylamino acids in proteins. By using a reversed phase HPLC system, we have developed a rapid and quantitative micro-identification method for amino-terminal acetylamino acids in...

- Micro-preparative polyacrylamide gel electrophoresis of basic proteins. LA-3848-MS.

- Microenvironmental regulation of biomacromolecular therapies. There is currently great interest in molecular therapies to treat various diseases, and this has prompted extensive efforts to achieve target-specific and...