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Nonlinear dynamics of paced cardiac cells.

Nonlinear dynamics of paced cardiac cells. Research Abstract Details 

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  • Nonlinear dynamics of paced cardiac cells. Abstract Text:

    yohannes shiferawYohannes Shiferaw,zhilin quZhilin Qu,alan garfinkelAlan Garfinkel,alain karmaAlain Karma,james n weissJames N Weiss,

    When a cardiac cell is rapidly paced it can exhibit a beat-to-beat alternation in the action potential duration (APD) and the intracellular calcium transient. This dynamical instability at the cellular level has been shown to correlate with the genesis of cardiac arrhythmias and has motivated the application of nonlinear dynamics in cardiology. In this article, we review mathematical approaches to describe the underlying mechanisms for alternans using beat-to-beat iterated maps. We explain the development and properties of these maps, and show that they provide a fruitful framework to understand dynamical instabilities of voltage and calcium in paced cardiac cells.

    Nonlinear dynamics of paced cardiac cells. Publishing Authors By Initials

    y shiferawY Shiferaw,z quZ Qu,a garfinkelA Garfinkel,a karmaA Karma,jn weissJN Weiss,

    For similar musculoskeletal system: muscles: myocardium research abstracts see: musculoskeletal system: muscles: myocardium research

    PUBMED ID PMID:

    MEDLINE DATE:

    Nonlinear dynamics of paced cardiac cells. Journal Published:

    PUBLICATION TYPE: Review

    Journal: Annals of the New York Academy of Sciences

    VOLUME: 1080

    Page Numbers: 376-94

    Journal Abbreviation: Ann. N. Y. Acad. Sci.

    ISSN: 0077-8923

    DAY: 3

    MONTH: Oct

    YEAR: 2006

    Nonlinear dynamics of paced cardiac cells. Information

    Number of References: 57

    LANGUAGE: eng

    NlmUniqueID: 7506858

    Nonlinear dynamics of paced cardiac cells. Keywords Mesh Terms:

    KEYWORDS: Myocardium

    MESH TERMS: metabolism

    Chemical & Substance for Abstract: Nonlinear dynamics of paced cardiac cells. Information

    Substance Name: Calcium

    Registry Number: 7440-70-2

    Grant and Affiliation Information for Nonlinear dynamics of paced cardiac cells.

    AFFILIATION: Division of Cardiology, David Geffen School of Medicine at UCLA, University of California-Los Angeles, Los Angeles, CA 90095, USA.

    Country: United States

    United States Research PublicationUnited States Research Publication

    AGENCY: United States NHLBI

    GRANT: P01 HL 078931

    ACRONYM: HL

    MEDLINETA: Ann N Y Acad Sci

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

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