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Glucose intolerance during hormonal therapy for prostate cancer.

Glucose intolerance during hormonal therapy for prostate cancer. Research Abstract Details 

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  • Glucose intolerance during hormonal therapy for prostate cancer. Abstract Text:

    k suzukiK Suzuki,a nukuiA Nukui,y haraY Hara,t moritaT Morita,

    The aim of this study was to examine the influence of hormonal therapy (HT) on glucose metabolism in prostate cancer (PCa) patients. Fifty-two PCa patients receiving HT with gonadotropin-releasing hormone (GnRH) analogues and/or antiandrogen drugs were enrolled in this study. Both blood and urine samples were taken a few hours after breakfast before and after HT, and glucose levels in the blood and urine were measured. Elevations of blood glucose levels of 30-50, 50-100 and over 100 mg/dl after HT as compared with the levels before HT were observed in two, eight and five patients, respectively. Urine examination revealed deterioration of glucosuria in seven patients. The mean blood glucose level after HT was significantly higher than that measured before HT. The elevation of blood glucose level significantly correlated with concurrence of diabetes mellitus (DM) and higher body mass index (BMI) before HT. Deterioration of glucosuria significantly correlated with the concurrence of DM. HT for PCa patients, especially with concurrent DM or obesity, induces elevation of the blood glucose level and deterioration of glucosuria. Therefore, glucose intolerance should be considered during HT for PCa.Prostate Cancer and Prostatic Diseases (2007) 10, 384-387; doi:10.1038/sj.pcan.4500976; published online 8 May 2007.

    Glucose intolerance during hormonal therapy for prostate cancer. Publishing Authors By Initials

    k suzukiK Suzuki,a nukuiA Nukui,y haraY Hara,t moritaT Morita,

    For similar abstracts research abstracts see: abstracts research

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    MEDLINE DATE:

    Glucose intolerance during hormonal therapy for prostate cancer. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Prostate cancer and prostatic diseases

    VOLUME: 10

    Page Numbers: 384-7

    Journal Abbreviation: Prostate Cancer Prostatic Dis.

    ISSN: 1365-7852

    DAY: 8

    MONTH: 05

    YEAR: 2007

    Glucose intolerance during hormonal therapy for prostate cancer. Information

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    LANGUAGE: eng

    NlmUniqueID: 9815755

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    Grant and Affiliation Information for Glucose intolerance during hormonal therapy for prostate cancer.

    AFFILIATION: [1] 1Department of Urology, Jichi Medical University, Tochigi, Japan [2] 2Department of Urology, Utsunomiya Shakaihoken Hospital, Tochigi, Japan.

    Country: England

    England Research Publication

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    MEDLINETA: Prostate Cancer Prostatic Dis

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