A patient developed frontal-lobe syndrome and psychotic symptoms after infarction in the pontomesencephalic junction. Stereotaxic lesion localization on magnetic resonance imaging and statistical analyses of regional cerebral blood flow (rCBF) disclosed an involvement of the rostral brainstem dopaminergic nuclei and hypoperfusion in the frontal-subcortical circuit components. We suggest that the patient's cognitive and behavioral disturbances were associated with disruption of ascending dopaminergic projections to the frontal-subcortical circuits.
Frontal-lobe syndrome and psychosis after damage to the brainstem dopaminergic nuclei. Publishing Authors By Initials
Frontal-lobe syndrome and psychosis after damage to the brainstem dopaminergic nuclei. Journal Published:
PUBLICATION TYPE: Research Support, Non-U.S. Gov
Journal: Journal of the neurological sciences
VOLUME: 260
Page Numbers: 271-4
Journal Abbreviation: J. Neurol. Sci.
ISSN: 0022-510X
DAY: 21
MONTH: 05
YEAR: 2007
Frontal-lobe syndrome and psychosis after damage to the brainstem dopaminergic nuclei. Information
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LANGUAGE: eng
NlmUniqueID: 375403
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Grant and Affiliation Information for Frontal-lobe syndrome and psychosis after damage to the brainstem dopaminergic nuclei.
AFFILIATION: Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University Graduate School of Medicine, Sendai, Japan. nishiou@mail.tains.tohoku.ac.jp
Country: Netherlands
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MEDLINETA: J Neurol Sci
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