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Clinical course of mesenteric artery stenosis in elderly americans.

Clinical course of mesenteric artery stenosis in elderly americans. Research Abstract Details 

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  • Clinical course of mesenteric artery stenosis in elderly americans. Abstract Text:

    david b wilsonDavid B Wilson,kian mostafaviKian Mostafavi,timothy e cravenTimothy E Craven,juan ayerdiJuan Ayerdi,matthew s edwardsMatthew S Edwards,kimberley j hansenKimberley J Hansen,

    BACKGROUND: To examine prospectively the relationship between stenosis or occlusion of the celiac and superior mesenteric arteries and symptoms of chronic intestinal ischemia in free-living elderly patients in the United States. METHODS: As part of an ancillary study to the Cardiovascular Health Study, participants in the Forsyth County (North Carolina) cohort underwent visceral duplex ultrasonography of the celiac and superior mesenteric arteries. Critical mesenteric artery stenosis (MAS) or occlusion was defined by Doppler flow ultrasound-derived criteria. Clinical outcomes were assessed at annual follow-up examinations and review of death certificates. Multivariate associations between the presence of MAS and all-cause mortality and adverse cardiovascular events were analyzed. Participants with MAS were contacted to determine the presence of symptoms consistent with chronic intestinal ischemia. RESULTS: Of 553 participants who underwent visceral duplex ultrasonography, 97 (17.5%) had disease of the celiac or superior mesenteric artery. At a mean follow-up of 6(1/2) years, 20 participants with MAS (20.6%) and 93 without MAS (20.4%) had died (relative risk, 1.01; 95% confidence interval, 0.66-1.55). No deaths were attributed to intestinal infarction. No association existed between the presence of MAS and prevalent cardiovascular disease, all-cause mortality, or adverse cardiovascular events. A questionnaire was completed by 71% of the surviving participants with MAS. No participant reported symptoms or weight loss consistent with chronic intestinal ischemia. CONCLUSIONS: Mesenteric artery stenosis was a common finding in free-living elderly patients. At long-term follow-up, the presence of asymptomatic MAS was not associated with death or adverse cardiovascular events. Participants with asymptomatic MAS by duplex ultrasonographic criteria did not experience intestinal infarction or develop chronic intestinal ischemia.

    Clinical course of mesenteric artery stenosis in elderly americans. Publishing Authors By Initials

    db wilsonDB Wilson,k mostafaviK Mostafavi,te cravenTE Craven,j ayerdiJ Ayerdi,ms edwardsMS Edwards,kj hansenKJ Hansen,

    For similar investigative techniques: epidemiologic methods: statistics as topic: probability: risk: risk factors research abstracts see: investigative techniques: epidemiologic methods: statistics as topic: probability: risk: risk factors research

    PUBMED ID PMID:

    MEDLINE DATE:

    Clinical course of mesenteric artery stenosis in elderly americans. Journal Published:

    PUBLICATION TYPE: Research Support, N.I.H., Extr

    Journal: Archives of internal medicine

    VOLUME: 166

    Page Numbers: 2095-100

    Journal Abbreviation: Arch. Intern. Med.

    ISSN: 0003-9926

    DAY: 23

    MONTH: Oct

    YEAR: 2006

    Clinical course of mesenteric artery stenosis in elderly americans. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 372440

    Clinical course of mesenteric artery stenosis in elderly americans. Keywords Mesh Terms:

    KEYWORDS: Risk Factors

    MESH TERMS: mortality

    Chemical & Substance for Abstract: Clinical course of mesenteric artery stenosis in elderly americans. Information

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    Grant and Affiliation Information for Clinical course of mesenteric artery stenosis in elderly americans.

    AFFILIATION: Division of Surgical Sciences, Section on Vascular and Endovascular Surgery, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

    Country: United States

    United States Research PublicationUnited States Research Publication

    AGENCY: United States NHLBI

    GRANT: N01-HC-85086

    ACRONYM: HC

    MEDLINETA: Arch Intern Med

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