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Cerebral hemodynamics during microgravity.

Cerebral hemodynamics during microgravity. Research Abstract Details 

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  • Cerebral hemodynamics during microgravity. Abstract Text:

    taro miyahara gotohTaro Miyahara Gotoh,kunihiko tanakaKunihiko Tanaka,nobuhiro fujikiNobuhiro Fujiki,tomoko matsudaTomoko Matsuda,shuang gaoShuang Gao,hironobu moritaHironobu Morita,

    As one of the causes of the space adaptation syndrome, an increased intracranial pressure due to the cephalad fluid shift is suggested. In the present study, we measured intracranial pressure (ICP), aortic pressure and cerebral flow velocity (CFV) in anesthetized rats (n=5) during 4.5 sec of microgravity induced by free drop. The rats were set at horizontal prone (Flat) and 30-degree head-up whole body tilting (HU) positions to examine the effect of gravitational pressure gradient. Then, arterial pressure at the eye level (APeye), cerebral perfusion pressure (CPP; CPP=APeye-ICP), and CPP-CFV relationship was calculated. In HU position, ICP, APeye, and CPP increased by 2.2 +/- 0.4, 12.3 +/- 2.0, and 10.1 +/- 1.7 mmHg respectively. However, CFV did not change significantly. In Flat position, none of these variables did not change significantly. In HU position the slope of CPP-CFV relationship decreased, suggesting the increased cerebral flow resistance. However, it did not change in Flat position. These results can be understood by the disappearance of gravitational pressure gradient by microgravity and the cerebral autoregulation.

    Cerebral hemodynamics during microgravity. Publishing Authors By Initials

    tm gotohTM Gotoh,k tanakaK Tanaka,n fujikiN Fujiki,t matsudaT Matsuda,s gaoS Gao,h moritaH Morita,

    For similar abstracts research abstracts see: abstracts research

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    Cerebral hemodynamics during microgravity. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Biological sciences in space = Uch? seibutsu kagak

    VOLUME: 17

    Page Numbers: 204-5

    Journal Abbreviation: Biol. Sci. Space

    ISSN: 0914-9201

    DAY: 16

    MONTH: Oct

    YEAR: 2003

    Cerebral hemodynamics during microgravity. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 100972048

    Cerebral hemodynamics during microgravity. Keywords Mesh Terms:

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    Grant and Affiliation Information for Cerebral hemodynamics during microgravity.

    AFFILIATION: Department of Physiology, Gifu University School of Medicine.

    Country: Japan

    Japan Research PublicationJapan Research Publication

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    MEDLINETA: Biol Sci Space

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