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[Resection of cancer of the cardia enabled by combined treatment with S-1 and paclitaxel after esophageal stenting for impaired patency complicating stage IV gastric cancer - a case report]

[Resection of cancer of the cardia enabled by combined treatment with S-1 and paclitaxel after esophageal stenting for impaired patency complicating stage IV gastric cancer - a case report] Research Abstract Details 

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  • [Resection of cancer of the cardia enabled by combined treatment with S-1 and paclitaxel after esophageal stenting for impaired patency complicating stage IV gastric cancer - a case report] Abstract Text:

    taigo tokuharaTaigo Tokuhara,toyokazu okudaToyokazu Okuda,chikaharu sakataChikaharu Sakata,masahiro nishikawaMasahiro Nishikawa,ryuhei moritaRyuhei Morita,taigo tokuharaTaigo Tokuhara,toyokazu okudaToyokazu Okuda,chikaharu sakataChikaharu Sakata,masahiro nishikawaMasahiro Nishikawa,ryuhei moritaRyuhei Morita,

    The patient was a 47-year-old man who was discovered to have Borrmann type 4 cancer of the cardiac region of the stomach associated with esophageal invasion during upper GI endoscopy and was histopathologically diagnosed with poorly-differentiated adenocarcinoma. Invasion of the aorta was suspected based on a CT examination, and resection was judged to be impossible. Since the tumor was associated with impaired patency, after first inserting a metallic stent, the patient was treated with 4 cycles of S-1 100 mg/body for 2 weeks and paclitaxel (PTX) 120 mg/body by intravenous drip infusion on days 1 and 15 for 2 weeks followed by a 2-week rest period. The tumor regressed considerably, and total gastrectomy and lower esophagectomy with D1+ a lymph node resection through a left thoracolaparotomy became possible. A bypass operation or palliative resection is sometimes performed when complicated by impaired patency. In our patient, after achieving an improvement in QOL by stenting, resection became possible as a result of a response to chemotherapy with S-1. However, when considering resection after chemotherapy it seemed necessary to be careful to insert the stent as close as possible to the proximal margin of the tumor so as not to broaden the extent of the esophageal resection.

    [Resection of cancer of the cardia enabled by combined treatment with S-1 and paclitaxel after esophageal stenting for impaired patency complicating stage IV gastric cancer - a case report] Publishing Authors By Initials

    t tokuharaT Tokuhara,t okudaT Okuda,c sakataC Sakata,m nishikawaM Nishikawa,r moritaR Morita,t tokuharaT Tokuhara,t okudaT Okuda,c sakataC Sakata,m nishikawaM Nishikawa,r moritaR Morita,

    For similar abstracts research abstracts see: abstracts research

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    [Resection of cancer of the cardia enabled by combined treatment with S-1 and paclitaxel after esophageal stenting for impaired patency complicating stage IV gastric cancer - a case report] Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Gan to kagaku ryoho. Cancer & chemotherapy

    VOLUME: 34

    Page Numbers: 1651-4

    Journal Abbreviation: Gan To Kagaku Ryoho

    ISSN: 0385-0684

    DAY: 17

    MONTH: Oct

    YEAR: 2007

    [Resection of cancer of the cardia enabled by combined treatment with S-1 and paclitaxel after esophageal stenting for impaired patency complicating stage IV gastric cancer - a case report] Information

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    LANGUAGE: jpn

    NlmUniqueID: 7810034

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    Grant and Affiliation Information for [Resection of cancer of the cardia enabled by combined treatment with S-1 and paclitaxel after esophageal stenting for impaired patency complicating stage IV gastric cancer - a case report]

    AFFILIATION: Dept. of Surgery, Asakayama General Hospital.

    Country: Japan

    Japan Research PublicationJapan Research Publication

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    MEDLINETA: Gan To Kagaku Ryoho

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